Pamoic acid
CAS No. 130-85-8
Pamoic acid( —— )
Catalog No. M21619 CAS No. 130-85-8
Pamoic acid is the orphan G protein-coupled receptor GPR35?agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NamePamoic acid
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NoteResearch use only, not for human use.
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Brief DescriptionPamoic acid is the orphan G protein-coupled receptor GPR35?agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
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DescriptionPamoic acid is the orphan G protein-coupled receptor GPR35?agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetGPR
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RecptorGPR35
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Research Area——
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Indication——
Chemical Information
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CAS Number130-85-8
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Formula Weight388.37
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Molecular FormulaC23H16O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (128.74 mM)
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SMILESOC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O
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Chemical Name44'-Methylenebis(3-hydroxy-2-naphthoic acid)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhao P Sharir H Kapur A et al. Targeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and Arrestin2 with Antinociceptive Activity[J]. Molecular Pharmacology 2010 78(4):560-568.
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